Scientists claim that simple changes in diet, exercise and sleep could reverse a person’s biological age in as little as eight weeks.
University of Virginia researchers asked six healthy women, around the age of 58, to follow a diet high in leafy greens, seeds and three servings of liver per week for two months.
The anonymous participants were also asked to exercise 30 minutes five days a week, sleep at least seven hours a night, and do two 10-minute breathing exercises daily.
The results showed that the women’s biological age – the estimated age of their cells – fell on average by almost five years, from 56 to 51 years. One participant’s biological age decreased by 11 years during the study, from 57 to 46 years.
Biohacking has become increasingly popular in recent years. Adherents seek to reduce their biological age — the age of their cells and tissues — in order to live longer and prevent diseases such as heart disease.
The women were asked to follow the above diet and lifestyle plan for eight weeks. Their blood was tested for biomarkers of aging at the beginning and end of the study
The diet is designed to support DNA methylation, which helps keep cells in the body healthy.
However, with age, DNA methylation generally becomes altered and less efficient, leading to faster aging of cells.
Researchers tracked how well participants followed the program. revealed in the magazine this year agingvia daily reports in one app.
Overall, participants adhered to the plan 82 percent of the time, but were more likely to stick to diet goals (84 percent) than lifestyle goals (77 percent).
The research team, led by aging expert Dr. Kara Fitzgerald said in the paper, “The results of this case series add to existing evidence suggesting that widely accessible, low-cost dietary and lifestyle interventions have been developed to support DNA methylation, and are widely considered safe, may be able to counteract measures by the reduce biological aging.
“This case series of female participants extends the previous pilot study of this intervention in males and suggests that beneficial biological age changes may be achievable in both sexes.”
For the diet, participants ate plenty of vegetables: Two cups daily of dark leafy greens like kale, spinach, and mustard, two cups of cruciferous greens like broccoli, and three cups of brightly colored vegetables like an eggplant.
They also received a daily serving of pumpkin and sunflower seeds, as well as half a cup of berries or half a teaspoon of rosemary or turmeric.
Everyone was asked to eat six pounds of meat daily and take probiotics and green powder supplements every 24 hours.
Participants were also told to consume three ounces of liver and five to 10 eggs per week.
For hydration, they were told to drink up to eight cups of water a day.
But they were also given instructions on which foods to avoid, namely those with added sugar or sweets, dairy products, grains, and legumes or beans.
The diet should be taken every day for a 12-hour period, which scientists say should be from 7 a.m. to 7 p.m.
Participants also had to make adjustments to their lifestyle. This included 30-minute, moderate-to-high-intensity exercise sessions five days a week, such as running or cycling, sleeping at least seven hours a night, and doing two 10-minute breathing exercises twice a day to combat stress.
At the beginning of the study, the participants had blood tests done to check their biological age.
This was estimated using the Horvath DNAmAge clock, which uses DNA methylation to estimate a person’s biological age. It is based on a sample of more than 8,000 adults.
To ensure compliance, participants had weekly sessions with trained nutritionists, who were available throughout the day to answer questions via an app.
They said their findings built on the previous study of men, which found their biological age changed by an average of three years after they followed the same diet every week.
However, the study had several limitations, one of which was that it was not clear which factor was responsible for the reduction in biological age.
Some scientists assume that this was probably a diet. However, previous research suggests that the effect is limited if someone is already eating well.
Others believe that changes in sleep habits and exercise programs can be much more powerful catalysts for promoting health.
Other limitations include the small sample size, so it was unclear whether another factor could have caused the reduction.
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